Publisher's Synopsis
Chromosomal defects are the most common cause of inherited disorders and are also responsible for a large proportion of miscarriages. These defects include transpositions, duplications, insertions, deletions, nondisjunction and other structural abnormalities.;This book is intended as a practical guide to such defects, their clinical significance, and the risks they pose for future pregnancies. Each chapter has two sections: biology and genetic counselling, the latter providing information intended to assist genetic counsellors and clients in deciding upon a course of action.;The guide is designed not only for counsellors and laboratory workers in cytogenetics, but also as a reference work for medical geneticists and other physicians.
