Publisher's Synopsis
Receptors initiate the means by which cellular regulators exert their actions on target cells. Because of the central role of cell-cell communication and signal transduction, receptors are of intrinsic interest to neuroscientists. Receptor studies utilize both traditional methods of analysis and modern molecular techniques.;This volume examines comprehensive protocols for "model" receptor techniques (radioligand binding, solubilization and purification). It also describes the methodology for the following receptors: bombesin/GRP, cholecystokinin, endothelin, fast nerve growth factor and gastrin-releasing peptide, insulin, insulin-like growth factors, interleukin 1, melanotropin, melatonin, natriuretic hormone, neurokinin, neurokinin, neurotensin, PACAP, pancreatic polypeptide, serotonin, steroids, transferrin and vasoactive peptides.
