Publisher's Synopsis
Research in the last few years has shown that deranged oncogenes or tumour suppressor genes play a major role in the development of many cancers. First discovered in obscure animal viruses and rare cancers, they have emerged over the past decade as key regulators of the growth and metabolism of normal cells. Defining the state of these genes is relevant to the diagnosis and prognosis of tumours. Now, the focus of attention is turning to ways of attacking abnormal oncogenes or replacing defective tumour suppressor genes as a new approach to the treatment of cancer.;In this book, the authors use the most up-to-date laboratory and clinical data to summarize our present understanding of the roles of these genes in cancer. They go on to describe the techniques available for studying these genes, their clinical relevance for diagnosis and prognosis, and ideas for turning this knowledge into useful clinical treatments.;Key references are given at the end of each chapter as well as suggestions for further reading. Two-colour illustrations are used throughout as an aid to clarity.
