Publisher's Synopsis
Written by an international group of noted basic scientists and clinicians, this volume presents state-of-the-art information on the mechanisms of action, pharmacology, neurophysiological effects, and therapeutic uses of botulinum neurotoxins. A major portion of the book reviews recent clinical experience and clinical trials with botulinum toxin therapy for strabismus, dystonia, juvenile cerebral palsy, spasticity, hyperhidrosis, gastrointestinal and genitourinary disorders, headache, cosmetic facial conditions, and various disorders involving excessive muscle contraction or pain. Other chapters examine the immunology of botulinum toxins, the use of other chemodenervating agents, and the development of novel neurotoxin constructs.
